Hyaluronic Acid / Sodium Hyaluronate is the key water maintaining substances in human skin. Found naturally in the second layer of the skin called the dermis,Hyaluronic Acid is a glycosaminoglycan,or simply described, a major component of the extra cellular matrix, responsible for the moisturizing and firming of skin. Holds up to 370% more moisture than even the Collagen protein molecule. Binds and retains essential moisture in the skin layers and reduces fine lines caused by dehydration.